1
Kafkas University, Faculty of Economics and Administrative Sciences, Kars, Turkiye
Abstract
Heart diseases remain one of the leading causes of death worldwide, highlighting the urgent need for fast, reliable, and effective diagnostic systems that enable early detection and intervention. This necessity has become more prominent with the increasing integration of digital transformation into the healthcare sector. In this context, advanced technologies such as Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL) have become integral components of clinical decision support systems. This study presents the development of a DL model based on Artificial Neural Networks (ANN) for the early diagnosis of heart disease. The dataset, comprising clinical and demographic characteristics of 303 individuals, was obtained from the open-source UCI platform. The data were preprocessed and divided into training and testing sets, and early stopping was applied during training to prevent overfitting. The developed model achieved an accuracy rate of 90.16%, demonstrating superior performance compared to traditional models. These findings suggest that AI and DL-based systems hold significant potential as reliable and effective decision support mechanisms in the healthcare field, particularly in the diagnosis of heart diseases, within the broader framework of digital transformation.
Yenikaya, M. A. (2025). Digital transformation in health: An artificial neural network-based prediction model. International Journal of Eurasia Social Sciences, 16(61), 1536–1555. https://doi.org/10.70736/ijoess.635
📄Agarwal, R., Gao, G., DesRoches, C., & Jha, A. K. (2010). Research commentary—The digital transformation of healthcare: Current status and the road ahead. Information Systems Research, 21(4), 796-809. https://doi.org/10.1287/isre.1100.0327
📄Ahamad, G. N., Shafiullah, Fatima, H., Imdadullah, Zakariya, S. M., Abbas, M., ... et al. (2023). Influence of optimal hyperparameters on the performance of machine learning algorithms for predicting heart disease. Processes, 11(3), 734. https://doi.org/10.3390/pr11030734
📄Choi, E., Schuetz, A., Stewart, W. F., & Sun, J. (2016). Using recurrent neural network models for early detection of heart failure onset. Journal of the American Medical Informatics Association, 24(2), 361–370. https://doi.org/10.1093/jamia/ocw112
📄Esteva, A., Kuprel, B., Novoa, R. A., Ko, J., Swetter, S. M., Blau, ... et al. (2017). Dermatologist-level classification of skin cancer with deep neural networks. Nature, 542(7639), 115-118. https://doi.org/10.1038/nature21056
📄Esteva, A., Robicquet, A., Ramsundar, B., Kuleshov, V., DePristo, M., Chou, K., ... et al. (2019). A guide to deep learning in healthcare. Nature Medicine, 25(1), 24-29. https://doi.org/10.1038/s41591-018-0316-z
📄García-Ordás, M. T., Bayón-Gutiérrez, M., Benavides, C., Aveleira-Mata, J., & Benítez-Andrades, J. A. (2023). Heart disease risk prediction using deep learning techniques with feature augmentation. Multimedia Tools and Applications, 82(20), 31759-31773. https://doi.org/10.1007/s11042-023-14817-z
📄Jabbar, M. A., Deekshatulu, B. L., & Chandra, P. (2013). Heart disease prediction using lazy associative classification. In 2013 International Mutli-Conference on Automation, Computing, Communication, Control and Compressed Sensing (iMac4s) (pp. 40-46). https://doi.org/10.1109/iMac4s.2013.6526381
📄Jan, M., Awan, A. A., Khalid, M. S., & Nisar, S. (2018). Ensemble approach for developing a smart heart disease prediction system using classification algorithms. Research Reports in Clinical Cardiology, 33-45. https://doi.org/10.2147/RRCC.S172035
📄Jiang, F., Jiang, Y., Zhi, H., Dong, Y., Li, H., Ma, S., ... et al. (2017). Artificial intelligence in healthcare: past, present and future. Stroke and Vascular Neurology, 2(4). https://doi.org/10.1136/svn-2017-000101
📄Jung, M. L., & Berthon, P. (2009). Fulfilling the promise: A model for delivering successful online health care. Journal of Medical Marketing, 9(3), 243-254. https://doi.org/10.1057/jmm.2009.26
📄Kingma, D. P., & Ba, J. (2015). Adam: A method for stochastic optimization. International Conference on Learning Representations (ICLR). https://doi.org/10.48550/arXiv.1412.6980
📄Kumar, M. N., Koushik, K. V. S., & Deepak, K. (2018). Prediction of heart diseases using data mining and machine learning algorithms and tools. International Journal of Scientific Research in Computer Science, Engineering and Information Technology, 3(3), 887-898.
📄Litjens, G., Kooi, T., Bejnordi, B. E., Setio, A. A. A., Ciompi, F., Ghafoorian, M., ... et al. (2017). A survey on deep learning in medical image analysis. Medical Image Analysis, 42, 60-88. https://doi.org/10.1016/j.media.2017.07.005
📄Mas, D., Massaro, M., Rippa, P., & Secundo, G. (2023). The challenges of digital transformation in healthcare: An interdisciplinary literature review, framework, and future research agenda. Technovation. https://doi.org/10.1016/j.technovation.2023.102716.
📄Muhammad, Y., Tahir, M., Hayat, M., & Chong, K. T. (2020). Early and accurate detection and diagnosis of heart disease using intelligent computational model. Scientific reports, 10(1), 19747. https://doi.org/10.1038/s41598-020-76635-9
📄Obermeyer, Z., & Emanuel, E. J. (2016). Predicting the future—Big data, machine learning, and clinical medicine. New England Journal of Medicine, 375(13), 1216-1219. https://doi.org/10.1056/NEJMp1606181
📄Rajkomar, A., Dean, J., & Kohane, I. (2019). Machine learning in medicine. New England Journal of Medicine, 380(14), 1347-1358. https://doi.org/10.1056/NEJMra1814259
📄Reddy, S., Fox, J., & Purohit, M. P. (2019). Artificial intelligence-enabled healthcare delivery. Journal of the Royal Society of Medicine, 112(1), 22-28. https://doi.org/10.1177/0141076818815510
📄Ripan, R. C., Sarker, I. H., Hossain, S. M. M., Anwar, M. M., Nowrozy, R., Hoque, M. M., … et al. (2021). A data-driven heart disease prediction model through K-means clustering-based anomaly detection. SN Computer Science, 2(2), 112. https://doi.org/10.1007/s42979-021-00518-7
📄Shickel, B., Tighe, P. J., Bihorac, A., & Rashidi, P. (2018). Deep EHR: A survey of recent advances in deep learning techniques for electronic health record (EHR) analysis. IEEE Journal of Biomedical and Health Informatics, 22(5), 1589-1604. https://doi.org/10.1109/JBHI.2017.2767063
📄Taylor, K., Properzi, F., Bhatti, S., & Ferris, K. (2020). Digital transformation—Shaping the future of European healthcare. United Kingdom: Deloitte Centre for Health Solutions.
📄Topol, E. (2019). Deep medicine: how artificial intelligence can make healthcare human again. Hachette UK.
📄Vîrgolici, O., & Virgolici, H. (2023). Predicting Prediabetes Using Simple a Multi-Layer Perceptron Neural Network Model. In ICIMTH (pp. 168-171). https://doi.org/10.3233/SHTI230453
📄Vrigazova, B. (2021). The proportion for splitting data into training and test set for the bootstrap in classification problems. Business Systems Research: International Journal of the Society for Advancing Innovation and Research in Economy, 12(1), 228-242. https://doi.org/10.2478/bsrj-2021-0015
📄Wang, Y., Kung, L., & Byrd, T. A. (2018). Big data analytics: Understanding its capabilities and potential benefits for healthcare organizations. Technological Forecasting and Social Change, 126, 3-13. https://doi.org/10.1016/j.techfore.2015.12.019
📄Xie, T., Liu, R., & Wei, Z. (2020). Improvement of the fast clustering algorithm improved by K-means in the Big Data. Applied Mathematics & Nonlinear Sciences, 5(1).